Pediatric ingredients

Osteopontin

Osteopontin - supporting immune maturation

The whey protein osteopontin has been identified in human milk, whereas only small quantities are present in bovine milk. As a consequence infant formulas have a significantly lower content of osteopontin than human breast milk which may impact areas like immune development.

Osteopontin is a heavily phosphorylated, acidic glycoprotein with strong calcium-binding properties. At Arla Foods Ingredients we can provide you with an 89% pure form of osteopontin, Lacprodan® OPN-10, the first osteopontin product on the market.

The research in osteopotin

Preliminary research suggests that osteopontin plays a part in the development of infant immune functions, promoting maturation of the immune system and protecting against pathogenic infections. The addition of Lacprodan® OPN-10 to an infant formula may encourage similar immune modulation in formula-fed infants compared to breastfed infants. It therefore could be the missing link in infant formulas to deliver immune protection similar to human milk.

Benefits associated with osteopontin:

  • Natural role in infant immune development
  • Induces expression of cytokines important for protective immunity
  • Reduces rotavirus severity

At Arla Foods Ingredients, we hold several patents for production and application of osteopontin.

Osteopontin - product range:

  • Lacprodan® OPN-10: osteopontin fractionated from bovine milk. Osteopontin content of protein is min  89% and 88% (as is) protein concentrate approx. dry matter

Osteopontin - awards:

 

 


Arla Foods Ingredients supports the WHO recommendation for exclusive breastfeeding for the first six months of an infant’s life and continued breastfeeding up to the age of two or beyond in combination with nutritionally appropriate complementary foods.