Scientific documentation is key to our pediatric ingredients

Scientific documentation is central to Arla Foods Ingredients’ Early life nutrition ingredient portfolio. We are committed to deliver safety and efficacy evidence of our ingredients for the infant formula industry by providing our customers highly developed and targeted pre-clinical and clinical evidence that can be integrated into their final product documentation.

Over the years, we’ve built a reputation for solid, evidence-based clinical research in the industry. This work is carried out in close collaboration with leading research partners to provide a solid understanding of the role and mechanism of our ingredients developed for early life nutrition.

Close attention to this aspect is an unwavering principle that has guided our development efforts and documentation investments for decades. At Arla Foods Ingredients, the Early life nutrition department is on a journey to discover and deliver science based ingredients that support early life nutrition.
Arla Foods Ingredients’ partnerships applies to market insights as well as our sales and marketing experts can contribute valuable industry and consumer insights to support product positioning efforts and accelerate time-to-market.

Science & Insights

Science focus areas

Surveys and studies

Highlighted Arla Foods Ingredients’ collaboration studies

Feeding infants formula with probiotics or milk fat globule membrane: a double-blind, randomized controlled trial

Content of n-3 LC-PUFA in breast milk four months postpartum is associated with infancy blood pressure in boys and infancy blood lipid profile in girls

Osteopontin in human milk and infant formula affects infant plasma ostepontin concentrations

Preclinical Brown Norway rat models for the assessment of infant formulas in the prevention and tretament of cow's milk allergy

The Impact of Immune Interventions: A Systems Biology Strategy for Predicting Adverse and Beneficial Immune Effects.

Fecal microbiome and metabolome of infants fed bovine MFGM supplemented formula or standard formula with breast-fed infants as reference: a randomized controlled trial

Metabolic phenotype of breast-fed infants, and infants fed standard formula or bovine MFGM supplemented formula: a randomized controlled trial

Effects of milk fat globule membrane and its various components on neurologic development in a postnatal growth restriction rat model

The enduring effects of early-life stress on the microbiota-gut-brain axis are buffered by dietary supplementation with milk fat globule membrane and a prebiotic blend

Bovine Milk Oligosaccharides with Sialyllactose Improves Cognition in Preterm Pigs

Hydrolyzed formula with reduced protein contents supports adequate growth: A randomized controlled non-inferiority trial

Osteopontin in human milk and infant formula affects infant plasma ostepontin concentrations

Satiety Factors Oleoylethanolamide, Stearoylethanolamide, and Palmitoylethanolamide in Mother's Milk Are Strongly Associated with Infant Weight at Four Months of Age-Data from the Odense Child Cohort

Effect of bovine milk fat globule membranes as a complementary food on the serum metabolome and immune markers of 6-11-month-old Peruvian infants

Serum, plasma and erythrocyte membrane lipidomes in infants fed formula supplemented with bovine milk fat globule membranes

The role of milk fat globule membranes in behavior and cognitive function using a suckling rat pup supplementation model

Milk Fat Globule Membrane Supplementation in Formula-fed Rat Pups Improves Reflex Development and May Alter Brain Lipid Composition

Early life diets with prebiotics and bioactive milk fractions attenuate the impact of stress on learned helplessness behaviours and alter gene expression within neural circuits important for stress resistance

Milk Fat Globule Membrane Inhibits NLRP3 Inflammasome Activation and Enhances Intestinal Barrier Function in a Rat Model of Short Bowel

Milk Fat Globule Membrane Attenuates High-Fat Diet-Induced Obesity by Inhibiting Adipogenesis and Increasing Uncoupling Protein 1 Expression in White Adipose Tissue of Mice

Mining Milk for Factors which Increase the adherence of Bifidobacterium longum subsp. Infantis to Intestinal Cells

Milk fat globule membrane supplementation modulates the gut microbiota and attenuates metabolic endotoxemia in high-fat diet-fed mice

Bioactive Whey Protein Concentrate and Lactose Stimulate Gut Function in Formula-fed Preterm Pigs

Effects of osteopontin-enriched formula on lymphocyte subsets in the first 6 months of life: a randomized controlled trial

Breastfeeding, infant formula, and introduction to complementary foods-comparing data obtined by questionnaires and helth visitors' reports to weekly short message service text messages

Milk Fat Globule Membrane Supplementation in Formula Modulates the Neonatal Gut Microbiome and Normalizes Intestinal Development

Dietary Prebiotics and Bioactive Milk Fractions Improve NREM Sleep, Enhance REM Sleep Rebound and Attenuate the Stress-Induced Decrease in Diurnal Temperature and Gut Microbial Alpha Diversity

Oral Microbiota in Infants Fed a Formula Supplemented with Bovine Milk Fat Globule Membranes - A Randomized Controlled Trial

Growth, nutrition, and cytokine response of breast-fed infants and infants fed formula with added bovine osteopontin

Prebiotics and Bioactive Milk Fractions Affect Gut Development, Microbiota, and Neurotransmitter Expression in Piglets

Dietary Prebiotics, Milk Fat Globule Membrane, and Lactoferrin Affects Structural Neurodevelopment in the Young Piglet

Early life diet containing prebiotics and bioactive whey protein fractions increased dendritic spine density of rat hippocampal neurons

Hydrolyzed whey protein prevens the development of food allergy to ß-lactoglobulin in sensitized mice

Infections in infants fed formula supplemented with bovine milk fat globule membranes

Pre-clinical in vitro and in vivo safety evaluation of bovine whey derived osteopontin, Lacprodan® OPN-10

Suppression of tumor growth by orally administered osteopontin is accompanied by alterations in tumour blood vessels

Bovine osteopontin modifies the intestinal transcriptome of formula-fed infant rhesus monkeys to be more similar to those that were breastfed

Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-protein formula supplemented with bovine milk fat globule membranes: a randomized controlled trial.

Safety and tolerance evaluation of milk fat globule membrane-enriched infant formulas: a randomized controlled multicenter non-inferiority trial in healthy term infants

Cardiovascular risk markers until 12 mo of age in infants fed a formula supplemented with bovine milk fat globule membranes

Raw bovine milk improves gut responses to feeding relative to infant formula in preterm piglets

Early supplementation of phospholipids and gangliosides affects brain and cognitive development in neonatal piglets

Whey protein processing influences formula-induced gut maturation in preterm pigs

Alpha-Lactalbumin and Casein-Glycomacropeptide Do Not Affect Iron Absorption from Formula in Healthy Term Infants

Bovine colostrum is superior to enriched formulas in stimulating intestinal function and necrotising resistance in preterm pig

Efficacy of an MFGM-enriched complementary food in diarrhea, anemia, and micronutrient status in infants

Early feeding in infancy and atopic dermatitis - a prospective observational study

Formula Feeding Skews Immune Cell Composition toward Adaptive Immunity Compared to Breastfeeding

Effects of alpha-lactalbumin–enriched formula containing different concentrations of glycomacropeptide on infant nutrition

The effects of alpha-lactalbumin and glycomacropeptide on the association of CaCo-2 cells by enteropathogenic Escherichia coli, Salmonella typhimurium and Shigella flexneri

Effects of Bovine alpha-lactalbumin and Casein glycomacropeptide-enriched infant formulae on faecal microbiota in healthy term infants

In vitro digestion of novel milk protein ingredients for use in infant formulas: Research on biological functions

Cow milk-specific humoral and cellular immune response in infants with high risk of atopy under feeding a whey hydrolysate infant formula

A two-stage continuous culture system to study the effect of supplemental alpha-lactalbumin and glycomacropeptide on mixed cultures of human gut bacteria challenged with enteropathogenic Escherichia and Salmonella serotype Typhimurium

rRNA Probes Used to Quantify the Effects of glycomacropeptide and alpha-lactalbumin supplementation on the predominat groups of intestinal bacteria of infant rhesus monkeys challenged with Enteropathogenic Escherichia coli

Glycomacropeptide and alpha-lactalbumin supplementation of infant formula affects growth and nutritional status in infant rhesus monkeys

Use of batch culture and a two-stage continuous culture system to study the effect of supplemental alpha-lactalbumin and glycomacropeptide on mixed population of human gut bacteria

Early life nutrition news

Pre-clinical in vitro and in vivo safety evaluation of bovine whey derived osteopontin, Lacprodan^® OPN-10