Medical nutrition

Inflammatory bowel disease

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Animal studies have indicated that casein glycomacropeptide (CGMP) may help reduce disease activity in IBD patients.

Arla Foods Ingredients supplies Lacprodan® CGMP, unique ingredients with a high content casein glycomacropeptide, naturally produced from milk.

In a recent human study, researchers investigated how our Lacprodan® CGMP was tolerated and accepted in patients with active ulcerative colitis (UC) and if the addition of Lacprodan® CGMP to the patient’s usual medical treatment (5’ASA) could improve the clinical course. Result showed that the addition of Lacprodan® CGMP as adjunct nutritional therapy to standard treatment was safe and well accepted by patients with active distal UC and that the disease-modifying effect of Lacprodan® CGMP-20 was similar to that of standard medical dose escalation.

Link to the publication, please click here.

Animal studies have indicated that part of the beneficial effects of CGMP can be attributed to:

  • Prebiotic effect which promote growth of beneficial microflora
  • High level of threonine which is important for formation of the protective mucus layer in the gastrointestinal tract
  • Pathogen decoy effect due to high sialic acid content

Products Casein glycomacropeptide